The One Codex Blog

One Codex at ASM Microbe '17

ASM Microbe, one of the largest microbiology conferences in the world, is right around the corner. With more than 10,000 attendees, it’s a great event to connect with the research community, learn the latest scientific advances, and introduce microbial genomics experts to the One Codex platform you have come to love. If you are attending the conference, please stop by ATCC’s booths (#2411 & 2413) to meet the One Codex team or send us a note.

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Announcing the Targeted Loci Database for 16S and other amplicon sequencing

Scientists that study the microbiome generally use two different methods to analyze samples – sequencing all of the DNA in a sample (whole genome sequencing) or targeting a specific marker gene (e.g., 16S, 18S, ITS). While whole genome sequencing (WGS) enables high-resolution taxonomic and functional characterization of microbiome samples, 16S sequencing is a cost effective technique for broad community surveys across large numbers of samples. Today, we’re excited to announce that One Codex is launching a powerful new tool for 16S and other amplicon sequencing – making high-quality, reference-based analysis of marker gene studies easier, faster, and more accessible.

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Targeted Loci Post (long)

People that study the microbiome generally use two different genomic methods to analyze samples – sequencing all of the DNA in a sample (WGS) or targeting a specific marker gene (e.g. 16S rDNA). While WGS provides a high-resolution taxonomic and functional characterization of microbiome samples, 16S sequencing is a cost effective technique for broad community surveys across large collections of samples. Today, I’m excited to announce that One Codex is launching a powerful tool for 16S analysis – which we hope will make high-quality 16S analysis more accessible to a broad range of researchers.

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Notebooks (and more!)

Today, we’re extremely excited to announce several new features we’ve been working on for the past few months. Collectively, these should make it both easier and faster to perform custom, large-scale analyses, explore your data, and build applications atop the One Codex platform: A new easier-to-use, more powerful API (read the docs) A new version of our command-line interface and an accompanying Python client library for quickly getting started with the new API (take a peek on Github) And last but not least – interactive notebooks built directly into the platform!

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Running new analyses & whole-genome alignments

Today we’d like to tell you about a new feature on One Codex that allows you to run new analyses against your samples, including AMR gene panels and whole-genome alignments. Running New Analyses When samples are uploaded to One Codex, we automatically classify them using the One Codex Database of ~40K complete microbial genomes. However, metagenomic classification is just one of a range of microbial analysis tools provided by the One Codex platform.

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